Peter F Arndt is a Research Group Leader at the Max Planck Institute for Molecular Genetics in Berlin
Peter received a Diploma in Physics in 1995 and a PhD in Theoretical Physics in 1998 at Bonn University. He did postdoctoral work at Cologne University, the Kavli Institute for Theoretical Physics in Santa Barbara, and the University of California in San Diego. He is a frequent visitor of the Department of Biology at Stanford University and the Cancer Program at the Broad Institute in Boston.
The prevalent topic of interest in the Arndt Lab is the evolution of eukaryotic genomes, especially the modelling of processes that change the DNA. These processes encompass single nucleotide exchanges, insertions and deletions of short segments of DNA (due to slippage), insertions of repeats, segmental duplications, and whole genome duplications. All these processes left distinct marks in present day genomes, which we set out to investigate. For such an analysis different data sources are at our disposal. We are interested in the dynamics of such processes over evolutionary time scales, i.e. over millions of years. We use available data on the divergence of genomic sequences between species, as well as data on variations between individuals within one population.
Nowadays evolution can also be studied on much shorter time scales, for instance during the development of a tumor out of healthy tissue. Due to advances in next generation sequencing technologies and the availability of vast amounts of sequence data in public databases this analysis is possible with more power and precision than before.
In the role of Faculty Member, Peter Arndt contributes recommendations and reviews to the Computational Genomics & Genetic Analysis Section in the Bioinformatics, Biomedical Informatics & Computational Biology Faculty, writing brief accessible comments to summarize the value of the articles and adding rating score.
The Faculty comprises Heads of Faculty, Heads of Section, Faculty Members and Associate Faculty Members, as well as an International Advisory Board.
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