Jeff Sands - F1000 Section Head (since 10 January 2005)
Renal Division, Emory University, Atlanta, GA, USA
BIOGRAPHY
EDUCATION:1973-1977 - B.A. summa cum laude, Applied Mathematics, Harvard College
1977-1981 - M.D., Boston University School of Medicine
1981-1983 - Resident in Internal Medicine (PGY1-2), University of Chicago, Chicago, IL
1983-1986 - Medical Staff Fellow (PGY3-5), NHLBI, NIH, Bethesda, MD
1986-1988 - Senior Staff Fellow (PGY6-7), LKEM, NHLBI, NIH, Bethesda, MD
1988-1989 - Fellow in Nephrology (PGY8), Emory University Hospitals, Atlanta, GA
MEMBERSHIPS:
1985 American Society of Nephrology
1986 American Federation for Medical Research
1986 International Society of Nephrology
1987 American Physiological Society
1987 Southern Salt, Water, and Kidney Club
1990 American Heart Association
1990 National Kidney Foundation
1991 Southern Society for Clinical Investigation
1994 American Society for Clinical Investigation
2001 Association of American Physicians
2009 American Clinical and Climatological Association
RESEARCH INTERESTS:
Dr. Sands' research is directed at understanding the physiology of the renal inner medulla and the urine concentrating mechanism. He is currently studying the molecular physiology of urea transporters and water channels. Dr. Sands uses a combination of isolated perfused tubule studies to measure transport, antibodies to measure changes in the abundance, phosphorylation, or location of the transport proteins in kidney tissue, and cell culture models to explore signaling pathways that regulate transport. Studies are performed in rats treated to produce physiological and pathophysiological models of human conditions, and in genetically engineered mice. Research areas being addressed include: 1) long-term regulation of urea transport proteins in rat models of human diseases such as diabetes; and 2) signaling mechanisms by which vasopressin rapidly regulates urea transport.