Renal, Fluid & Electrolyte Physiology

BIOGRAPHY

RESEARCH INTERESTS

I have been an investigator in the field of epithelial physiology for fifteen years having completed undergraduate training at the University of Otago in New Zealand and my doctoral training at the University of Adelaide in Australia. I have published my research in a number of areas including cystic fibrosis, regulation of the epithelial sodium channel (ENaC), the function of aquaporins and urea transporters and the structure of cell membranes. Currently my research focuses on the mechanisms by which the urothelium, which lines the surface of the urinary bladder, senses filling and ultimately, fullness. Little is known about mechanosensation and mechanotransduction in the bladder and the critical pathways of molecular communication, which allow normal voiding function.