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Control of Gene Expression

Photo of Roy Long

Roy Long - F1000 Faculty Member (since 14 December 2001)

Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, Milwaukee, WI, USA

BIOGRAPHY

ACADEMIC POSITION:
Associate Professor, Microbiology and Molecular Genetics, Medical College of Wisconsin

EDUCATION:
PhD: Pennsylvania State University (1994) Biological Chemistry

MEMBERSHIPS:
• American Association for the Advancement of Science (AAAS)
• American Society for Cell Biology (ASCB)
• RNA Society

HONORS/AWARDS:
Pew Scholar in the Biomedical Sciences

RESEARCH INTERESTS:
Using genetic, biochemical and cell biological approaches in the yeast S. cerevisiae, my laboratory is interested in studying mechanistic details of RNA localization, a process which post-transcriptionally regulates gene expression. In yeast ASH1 mRNA is localized to the distal end of the daughter cell during anaphase of the cell cycle, resulting in the exclusive deposition of Ash1p in daughter nuclei. Ash1p is a transcriptional repressor, and asymmetric sorting of Ash1p results in asymmetric regulation of transcription.

EVALUATIONS