Autoimmunity

BIOGRAPHY

Luciano Adorini, MD, has conducted postdoctoral studies at the University of California at Los Angeles under the supervision of Prof. Eli Sercarz. He has then directed a research unit at the Preclinical Research Center, Sandoz Pharma Ltd., Basel and has been Associate Director of Roche Milano Ricerche, Milano. He is presently Chief Scientific Officer at BioXell in Milano, a spin-off of Hoffmann-La Roche of which he is a co-founder.

Dr. Adorini has studied several aspects of antigen recognition by T cells and has analyzed immunoregulatory mechanisms to develop immunosuppressive strategies applicable to the treatment of autoimmune diseases. He has made significant contributions in the field of antigen presentation, peptide-MHC interactions and in the use of synthetic peptides to selectively modulate immune responses in vivo. His current interests are focused on the role of antigen presenting cells in immunoregulation, and on the pathogenesis and treatment of autoimmune diseases.