Acute Renal Failure

BIOGRAPHY

ACADEMIC POSITION:
Professor and Chair, Department of Pharmaceutical and Biomedical Sciences, South Carolina College of Pharmacy

EDUCATION:
• Saint Louis College of Pharmacy, Bachelor of Science in Pharmacy, 1980
• University of Arizona, Doctor of Philosophy, 1984

RESEARCH INTERESTS:
The research foci of my laboratory are directed towards understanding the signaling pathways of cell injury, death (apoptosis and necrosis) in epithelial and cancer cells, and regeneration of epithelial cells following injury. This research is particularly important since stroke, trauma, and heart and kidney failure result from cell injury and death. In turn, the ability of injured cells to repair and regenerate is key for the return of brain, heart and kidney function. In contrast, cancer cells exhibit alterations in cell death pathways that allow them to survive and multiply. Our goal is to develop selective therapeutic agents that prevent cell death and promote cell repair in epithelial cells and stimulate cell death in cancer cells.