Technology & Monitoring in Anesthesiology

BIOGRAPHY

Dr. Rampil, MD Professor of Anesthesiology and Neurological Surgery has been active in anesthesia research for more than twenty years and is the department's Director of Clinical Research, Course Director for the Resident Research Course and the Director of the Department of Anesthesia's Journal Club. He has been a pioneer in developing clinically relevant neurophysiologic monitoring systems and in computer-based data acquisition and signal processing systems. Dr. Rampil has conducted a number of highly cited clinical trials involving inhaled anesthetic agents and was the principal investigator for the FDA phase one trial of des¿urane. Dr. Rampil's current interest involves the mechanisms and sites of general anesthetic action. He made the seminal observation that surgical immobility (lack of movement response to surgical incision) was mediated by spinal sites, not in the cerebrum. He was a member of a multicenter NIH program project investigating the molecular mechanisms of anesthesia which has discovered speci¿c sites in ligand-gated ionophores which selectively block anesthetic effect. His most recent work involves the molecular mechanisms by which volatile anesthetics create surgical amnesia. This project uses proteomic and DNA microarray technology to examine how anesthetics act within the amygdala and other limbic areas to block the protein synthesis required for long term memory. Dr. Rampil was a Principal Investigator of a $7 million federal grant to design, build and test new imaging technologies which will work on awake, unrestrained animals. He has leadership roles in several national and international anesthesia societies and has served on the editorial boards of several major journals. Dr. Rampil is a member of the following Editorial Boards;Anesthesiology, Anesthesia&Analgesia, Journal of Clinical Monitoring, J App Physiol (Modeling section), J Neurosurg AnesthMajor Committee involvement;Chair, World Federation Anaesthesia Societies Technology Committee, ASA Electronic Media and Information Technology committee, and Anesthesia Patient Safety Foundation Committee on Scientific Review.