Biocatalysis

BIOGRAPHY

Currently on Sabbatical

ACADEMIC POSITION:
Professor, Department of Chemistry and Biochemistry, University of Colorado

EDUCATION:
• PhD Brandeis University, 1986
• Postdoctoral Fellow, Pennsylvania State University, 1986-88

AWARDS:
• American Cancer Society Junior Faculty Research Award, 1991-1994
• National Research Service Award, 1987

RESEARCH INTERESTS:
Professor Kuchta's group is primarily interested in the broad area of mechanistic enzymology. Their studies are directed towards understanding enzymic catalysis at the level of individual steps in the reaction pathway. To accomplish this, a variety of steady-state and pre-steady-state kinetic techniques, protein modification reagents, and inhibitors are employed. We are primarily focusing on enzymes involved in
DNA replication from a variety of sources, including humans, herpes and bacteria.