Developmental Molecular Mechanisms

BIOGRAPHY

ACADEMIC POSITION:
Head of Laboratory of Systems Biology and Genetics, Life Sciences, Institute of Bioengineering, Ecole Polytechnique Federale de Lausanne (EFPL), Lausanne, Switzerland

RESEARCH INTERESTS:
Gene regulatory networks play a vital role in metazoan development and function, and deregulation of these networks is often implicated in disease. The interactions between genes and their respective regulatory transcription factors (TFs) that form the basis of gene regulatory networks have however been poorly characterized. This is because the transcriptional function of most metazoan TFs, which denotes the regulatory elements they bind to, the genes they regulate, the transcriptional consequence of their DNA interactions, and the transcriptional complexes in which they function, remains unknown.

The overall goal of our laboratory is to reverse engineer the gene regulatory networks that control metazoan development and function.