Hamid Rabb - F1000 Head of Faculty (since 16 November 2005)
Kidney Transplant Program, Johns Hopkins University School of Medicine, Baltimore, MD, USA
BIOGRAPHY
Hamid RabbAcademic positions:
- Physician Director of the Johns Hopkins Kidney and Pancreas Transplant Program
- Professor of Medicine
Any industry positions (last five years):
None declared
Research interests:
Dr Rabb's team has been involved in translational research to elucidate the molecular pathogenesis of kidney IRI in order to develop novel diagnostics and therapies. Specifically, they are investigating the role of cellular immunity in kidney IRI, a new area of investigation that fuses immunology, molecular biology and physiology. They have recently found that the T cell, within hours, is an important mediator of distant inflammation during the innate immune response to ischemia. Identification of immediate allo-antigen independent effects of T cells is a new field of investigation with considerable clinical relevance. His lab is using transgenic mouse models of kidney IRI to understand how T cells mediate the injury response at the cellular and molecular level. In addition, with the development of new technologies such as genomic and proteomic evaluation of cells, they are incorporating these tools, as well as expanding their research on T cells in kidney IRI to include cross talk between failing organs. They validate their lab findings in ongoing clinical models, and modify lab study design according to those clinical findings.
Any other information:
Dr Rabb frequently serves on NIH study sections, has served on the American Society of Nephrology program committee, and was past chair of scientific studies for the American Society of Transplantation.
He was awarded Fellow of the Royal College of Physicians (1991) and Fellow of the American College of Physicians (1995)
