Biomacromolecule-Ligand Interactions

BIOGRAPHY

EDUCATION:
• BS, Chemistry, University of Michigan, Ann Arbor, MI, 1965
• PhD, Chemistry, University of Cincinnati, Cincinnati, OH, 1969

MEMBERSHIPS/AWARDS:
Selected awards, honors & invited lectures:
• Award for WNY Health Care Technology/Discovery, Annual Health Care Industries Association Awards for Excellence in Western New York Health Care (3/94)
• Co-organizer of the First (1985 Buffalo, NY), Second (1987 Strasbourg, France), and Third (1989 Singapore) International Symposium of Flavonoids in Biology and Medicine
• Richard J Winzler Lecturer, Florida State University (1989)
• American Cancer Society Faculty Research Award, (1985-1990)
• Outstanding Woman in Science, WNY, SUNY-Community Service Award (1986)
• Visiting Scientist, LaTrobe University, Melbourne, Australia (3/85–5/85)
• New York State Woman of Distinction Award, (2001)
• Outstanding Alumna, Lake Superior State College, Sault Ste. Marie, Michigan (1975)
Professional memberships & activities:
• Editorial Board, Endocrinology
• Editorial Board, Endocrine Research
• GRIP Advisory Board, Computer Sciences Department, University of North Carolina, Chapel Hill, 1990-present
• Member, Nominating Committee, American Thyroid Association, 1997-present
• Member, Chemistry Task Force, American Association for Cancer Researchers

RESEARCH INTERESTS:
Current structural projects:
• Dihydrofolate reductase (DHFR) inhibitor complexes
• Histidine triad nucleotide binding proteins (Hint)
• Beta sliding clamp complexes with polymerase fragments for DNA repair
• Computational models of integrin-thyroid hormone interactions to design non-genomic hormone analogues
• GTP cyclohydrolase I isoforms and mutants from Drosophila