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Acute Renal Failure

Photo of Christof Westenfelder

Christof Westenfelder - F1000 Faculty Member (since 26 June 2008)

Division of Nephrology, Department of Internal Medicine, University of Utah Medical Centers, Salt Lake City, UT, USA

BIOGRAPHY

ACADEMIC POSITIONS:
• Professor of Medicine
• Chief, Renal Section VA Medical Center

RESEARCH INTERESTS:
The overall research focus of Dr Westenfelder's research is on the pathophysiology and treatment of acute renal failure. There is a particular emphasis on the role of erythropoietin (EPO) in acute renal failure, which has been identified by Dr Westenfelder as a renotropic cytokine. In addition, his group has found that EPO has additional importance in kidney cancer, polycystic kidney disease, acquired cystic kidney disease, and uremic encephalopathy. Besides the role of EPO in acute renal failure, Dr Westenfelder has demonstrated that bone marrow-derived stem cells possess kidney specific plasticity (are able to differentiate into renal cells), and when administered to rats with acute renal failure, act renoprotectively (appear to function as kidney precursor cells.

EVALUATIONS