Austin Hughes - F1000 Faculty Member (since 22 January 2003)
Department of Biological Sciences, University of South Carolina, Columbia, SC, USA
BIOGRAPHY
ACADEMIC POSITIONS:• Professor of Biological Sciences, University of South Carolina
• Director, Institute for Biological Research and Technology
EDUCATION:
PhD 1984, Indiana University
RESEARCH INTERESTS:
The goal of our research is to use statistical analysis of DNA sequence data from a wide variety of systems as a means of understanding the mechanisms of adaptive evolution, with emphasis on genes of the vertebrate immune system. We address the following specific questions:
(1) What is the mechanism maintaining polymorphism at the loci of the vertebrate major histocompatibility complex (MHC)?
(2) What molecular mechanisms have parasites evolved to evade recognition and attack by the vertebrate immune system?
(3) How do members of multigene families evolve new functions?
EVALUATIONS
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