Protein Chemistry & Proteomics

BIOGRAPHY

ACADEMIC POSITION:
Associate Professor and Principal Investigator, Bogyo Lab, Department of Pathology, Stanford University, CA

EDUCATION:
1997 PhD in Biological Chemistry, MIT, Cambridge, MA
1993 BS, Bates College, Lewiston, ME

AWARDS AND FELLOWSHIPS:
2008 Strategic Program for Asthma Research – Early Excellence Award
2005 Burroughs Wellcome Fund – Investigators in Pathogenesis of Infectious Disease Award
2004 Searle Scholar Award
2003 Recipient of Stanford University Terman Fellowship
1995 Recipient of MIT-Japan Science and Technology Prize
1992 American Chemical Society-Division of Polymer Chemistry award for organic synthesis
1992 American Institute of Chemists award for outstanding performance in chemistry
1991–1993 Recipient of pre-doctoral fellowships from Council on Undergraduate Research

RESEARCH INTERESTS:
Proteases play key roles in the regulation of normal and pathological processes ranging from cell division to invasion of a host cell by a pathogen. Our laboratory is interested in developing and applying chemical tools to dissect the functional roles of proteases in a number of human health conditions. Our research group is made up of a mix of synthetic organic chemists, biochemists, and cell biologists. We are currently using synthetic chemistry to build new reagents that allow protease activity to be monitored in complex biological samples including cells, tissues and whole animals. We are applying these tools to 1) functional studies of cysteine and serine proteases in the life cycle stages of the human parasites Toxoplasma gondii and Plasmodium falciparum 2) in vivo imaging of multiple classes of proteases during the process of tumorigenesis.