Methods for Diagnostic & Therapeutic Studies

BIOGRAPHY

ACADEMIC POSITION:
Academic staff, Assistant professor, Department of Epidemiology, UMC Utrecht

EDUCATION:
Yvonne Vergouwe obtained her degree in Biomedical Sciences at Leiden University (1996). In 1998 she started as a PhD student at the Department of Public Health of the Erasmus University Rotterdam. She defended her thesis ‘Validation of clinical prediction rules: theory and applications in testicular germ cell cancer’ in 2003. In 2004 she obtained a post-doc position at the Julius Centre for Health Sciences and Primary Care of the University Medical Centre Utrecht. In 2006 she visited the Centre for Statistics in Medicine, Oxford UK, head Professor Doug Altman. Since 2006 she is appointed as assistant professor of Clinical Epidemiology at the Julius Centre.

RESEARCH INTERESTS:
Yvonne Vergouwe’s research focuses on clinical prediction rules. Methodological issues include the use of methods to develop prediction rules (genetic programming, polytomous logistic regression), methods to validate and update prediction rules and multiple imputation in prediction research. Medical fields of application include oncology (testicular cancer), pediatrics (RSV infection, bacterial meningitis), anesthesia (postoperative nausea and vomiting, postoperative pain), internal medicine (deep venous thrombosis).