Biomacromolecule-Ligand Interactions

BIOGRAPHY

ACADEMIC POSITION:
Full Professor of Molecular Biology, University of Pavia

EDUCATION:
• 1988 University of Pavia (Italy), Biology Degree
• 1988-1992 University of Groningen (Netherlands), PhD
• 1992-1993 MRC-LMB, Cambridge (UK), Post-doc

MEMBERSHIPS/AWARDS:
• 1992 EMBO Long-Term Fellowship
• 2002-2004 EMBO Young Investigator
• June 2005 'Premio Borgia' awarded by 'Accademia dei Lincei, Rome'

RESEARCH INTERESTS:
The common theme to Dr Mattevi's research projects has been the investigation of medically relevant enzymes with interesting chemical properties, such as complex multifunctional systems and proteins performing unusual catalytic functions. The core of the research activity is represented by X-ray crystallography, employed to study protein three-dimensional structures. This is, however, complemented by other approaches such as site-directed mutagenesis, analysis of enzyme kinetics and computational chemistry.