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Figure 1.
Ribozyme structural descriptors
The structural descriptors of the (a) hammerhead and (b) hepatitis delta virus (HDV) ribozymes are shown mapped onto their respective two- and three-dimensional structures [9,11]. Nucleotides in red are fixed in the pattern. The nucleotides in grey denote fixed secondary structure but variable identity. Variable loops are represented with dashed lines. These images were constructed from coordinate files for the hammerhead (2GOZ) and HDV (1CX0) ribozymes. |
