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Figure 1.

Representation of the CRISPR (clustered regularly interspaced short palindromic repeats)-Cas system in archaeal and bacterial lineages

The bars show the fractions of sequenced genomes in each group that possess CRISPR-Cas (red) and lack CRISPR-Cas (blue). The actual numbers of available genomes are also indicated for both parts of each bar. The figure is based on the results of screening of the proteins encoded in 774 archaeal and bacterial genomes for statistically significant sequence similarity to Cas1 sequences using BLASTP [32].