• American Cancer Society Professor
• Distinguished Professor, Department Microbiology and Molecular Genetics
The Chang-Moore Laboratory in the Cancer Virology Program at the University of Pittsburgh Cancer Institute is responsible for discovering the viral causes of four different human cancers. In 1994, Chang-Moore lab identified and isolated Kaposi’s sarcoma-associated herpesvirus (KSHV) causing this epidemic cancer among HIV/AIDS patients (listen to a description of KSHV discovery). In addition to KS, KSHV causes primary effusion lymphoma (PEL) and most cases of multicentric Castleman’s disease (MCD). The Chang-Moore lab also developed a new technology (digital transcriptome subtraction, or DTS) for identifying human cancer viruses and in 2008 discovered Merkel cell polyomavirus (MCV) causing most Merkel cell carcinomas. Drs Moore and Chang are a husband and wife research team.
Research in the Chang-Moore laboratory ranges from basic biological investigations into how cells become cancerous to epidemiologic/clinical research into the diagnosis, treatment and prevention of cancers caused by viruses.
Department of Microbiology & Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA
Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA
University of Wisconsin-Stevens Point, Stevens Point, Wisconsin, USA
Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA
Chang-Moore Laboratory, Cancer Virology Program, University of Pittsburgh, Pittsburgh, PA, USA
In the role of Faculty Member, Patrick S Moore contributes recommendations and reviews to the Virology Section in the Microbiology Faculty, writing brief accessible comments to summarize the value of the articles and adding rating score.
The Faculty comprises Heads of Faculty, Heads of Section, Faculty Members and Associate Faculty Members, as well as an International Advisory Board.
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