Victor Hsu

BIOGRAPHY

ACADEMIC POSITIONS:
• Associate Professor, Department of Medicine, Harvard Medical School
• Associate Immunologist, Rheumatology, Immunology and Allergy, Brigham And Women's Hospital

RESEARCH INTERESTS:
We are interested in understanding mechanisms of vesicular transport and are also applying these insights to elucidating physiology and disease mechanisms. Coat proteins initiate, and thereby define, intracellular transport pathways. We have been studying the Coat Protein I (COPI) complex as a model system to understanding basic mechanisms of vesicle formation. We have also identified a new clathrin complex for endocytic recycling, a pathway critical for many cellular events. In recent years, we have discovered that COPI cooperates with critical lipids to “bend” the membrane bilayer in achieving vesicle formation. Our insights have also led us to elucidate molecular mechanisms that underlie cell migration, metabolic homeostasis, and viral pathogenesis.

HOME PAGE
http://www.hms.harvard.edu/dms/bbs/fac/hsu.html