Philip Murphy

BIOGRAPHY

CURRENT POSITIONS:
• Chief, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases
• Chief, Molecular Signaling Section, National Institute of Allergy and Infectious Diseases

MEMBERSHIPS/AWARDS:
• NIH Merit Award (1992)
• NIH Director's Award (1994, 1996)
• NIH Senior Biomedical Research Service (1998)
• American Society for Clinical Investigation (1992)
• Association of American Physicians (1997)
Memberships
• American Association for the Advancement of Science
• American Society for Cell Biology
• American Society for Clinical Investigation
• American Society of Biochemistry and Molecular Biology
• Association of American Physicians
• American Association of Immunologists
• Society for Leukocyte Biology

RESEARCH INTERESTS:
The Laboratory of Molecular Immunology (LMI) studies immune system function in health and disease and is especially interested in delineating mechanisms that control specific leukocyte movement. Research is conducted in the following areas:

• Molecular and cellular mechanisms of leukocyte trafficking in both innate and adaptive immunity with a focus on the chemokine family of chemoattractants
• G protein-coupled receptors of the immune system
• Mimics of chemotactic factors and their receptors in infectious agents, including HIV, herpesviruses, and poxviruses
• Structure and function of the mucosal immune system in the gut
• Basic properties of dendritic cells
• Molecular pathogenesis of complex infectious and immunologic/inflammatory diseases, including HIV/AIDS, West Nile virus infection, SARS, listeria infection, sepsis, atherosclerosis, Alzheimer's disease, and ischemia/reperfusion injury, with the goal of identifying novel therapeutic targets and vaccine strategies
• Genetic risk factors for complex immunologically mediated disease

HOME PAGE
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