Gary Aston-JonesDepartment of Neurosciences, Medical University of South Carolina, Charleston, SC, USA F1000 Faculty Member (since 06 July 2001)
Professor, Department of Neurosciences, Medical University of South Carolina
Murray Chair of Excellence in Neuroscience, Medical University of South Carolina
Director, Center for Cognitive Neuroscience, Medical University of South Carolina
Co-Director, Neuroscience Institute, Medical University of South Carolina
BA, Phil Theol, Biol Sci, 1973, University of Virginia, Charlottesville, VA
PhD, Neurobiology, 1980, California Institute of Technology, Pasadena, CA
Postdoctoral Fellow, Neurobiology, 1982, Salk Institute, San Diego, CA
On editorial board for Journal of Addiction Medicine, Brain Simulation. Board of Trustees Member for Gordon Research Conferences incorporated.
Dr Gary Aston-Jones' primary research interests are in the brain neuromodulatory systems, and their roles in cognitive performance, drug abuse, sleep and waking, and affective disorders. He uses a multidisciplinary approach, primarily involving single unit neurophysiology, neuroanatomy and behavioral neuropharmacology in rats and monkeys. He and his colleagues have recently described a role for the brain noradrenergic locus coeruleus system in decision processes, in the circadian regulation of sleep and waking, and in depression. Other of his lab's recent work also reveals a key role for the A1/A2 noradrenergic brain system innervation of the ventral forebrain in the affective response to drug withdrawal, and also indicates an important role of this and related systems in the drug seeking that accompanies protracted opiate withdrawal.
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