Michael IbrahimNational Heart & Lung Institute, Imperial College London, London, UK F1000 Associate Faculty Member (since 17 July 2009)
Michael Ibrahim is an Associate Faculty Member who works with Faculty Member Cesare Terracciano to recommend the scientific literature in their field.Michael Ibrahim also has responsibility for checking the contents of the following journals to ensure that the highest quality research relevant to their own interests within these publications is comprehensively and systematically evaluated for F1000:
- Philosophical Transactions of the Royal Society of London, B: Biological Sciences
- EMBO Reports
Michael Ibrahim is a medical student undertaking a PhD via the integrated MB-PhD programme at Imperial College.
I study the effects of chronic mechanical unloading on the structure and function of the excitation-contraction coupling machinery in the heart. This is an important clinical issue due to the increasing use of left ventricular assist devices which act predominantly by unloading the left ventricle. My hypothesis is that in the setting of chronic heart failure, initial improvements induced by mechanical unloading may be mediated by repair of the disrupted EC coupling machinery but that excessive unloading may damage this system.
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