Minesh MehtaDepartment of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA F1000 Faculty Member (since 03 April 2006)
Dr Mehta is a Professor of Radiation Oncology at the Feinberg School of Medicine.
EDUCATION AND BACKGROUND:
He obtained his medical degree at the University of Zambia in 1981 and commenced his residency there at the Ndola Central Hospital. He moved to the University of Wisconsin, Madison, in 1984 and completed his residency in radiation oncology in 1988 when he took up an Assistant Professorship in Human Oncology. He was then promoted to Associate Professor and became the Director of the Radiation Oncology Residency Training Program before becoming Interim Chair and then Chair of the department.
HONORS AND AWARDS:
2003, Best Physicians, Madison Business Magazine
2002, The Pancer Lecture, University of Toronto & Princess Margaret Hospital
2002-2004, Top Docs, Madison Magazine
2001, 15th Annual Simon Kramer Lecture, Thomas Jefferson University
1999, Nick Khadiwala Award for Excellence in Neuro-Oncology, Colorado Neurological Institute
1998-1999, The Best Doctors, The Best Doctors In America
1998-2003, Meet the Professors, ASTRO
1996, Radiotherapy Teacher of the Year, University of Wisconsin
1996-1999, The Best Doctors In America, Midwest Region
1995, Year Book, Oncology
1994, Dean's Teaching Award, University of Wisconsin
1993, Most Important Papers, International Monitor in Oncology
1992, ASTRO Travel Reserach Award, ASTRO
1992, Outstanding Article in the Field, Respiratory Diseases Digest
1990, Radiotherapy Teacher of the Year, University of Wisconsin
1990, Year Book, Otolaryngology
1989-2001, Physicians' Recognition Award, AMA
1981, Raymond Radunski Award, University of Zambia, Best Overall Medical School Graduate
1981, Merck Sharpe and Dohme Prize, University of Zambia, Best Graduate, Internal Medicine
1981, Upjohns Prize, University of Zambia, Best Graduate, Pediatrics
1981, Hassim Lucas Prize, University of Zambia, Best Graduate, Obstetrics and Gynecology
1980, Billingsley Award, University of Zambia, Best Medical Student
1978, Highest Scoring BSc Degree, University of Zambia
1975, Wildlife Conservation Prize, University of Zambia, Best Biology Freshman
1975, Kerry Gill Prize, University of Zambia, Best Chemistry Freshman
Dr Mehta is a fellow of the American Society of Radiation Oncology. He is a member of several national and international medical societies.
My research interests are primarily in the areas of tomotherapy, incorporating advanced imaging in radiotherapy treatment planning, CNS malignancies, lung cancer, pediatric neoplasms, stereotactic radiosurgery, radiosensitization, combined modality therapies, altered fractionation, cost-effectiveness, and outcomes research. I was the PI of a completed NIH-funded Program Project Grant.
Within the context of CNS neoplasms, my particular expertise is in setting up and running multi-disciplinary clinics, conducting national multimodality protocols, participating in national organizational strategies for managing these tumors and developing radiosurgery systems and protocols. In addition, within this context, I have developed 3-D/conformal techniques as well as interstitial brachytherapy expertise. I have run numerous multimodality clinical trials at the national level for both adult and pediatric CNS neoplasms. Current major thrust areas include developing molecularly-targeted agents as radiosensitizers for CNS tumors, such as the EGFR pathway, PKC, angiogenesis, etc.
I was the PI for a completed international Phase III trial of Motexafin-Gadolinium, a novel radiosensitizer, being evaluated in brain metastases patients. I am engaged in clinical trials combining Temozolomide with radiation therapy for CNS tumors. In addition, I am working with topoisomerase I inhibitors as radiosensitizers, for thoracic neoplasms, particularly small cell lung cancer. For the latter, I have developed a unique hyperfractionated, accelerated regimen, which has been tested in a national trial.
As far as pediatric neoplasms are concerned, my major research focus has been on medulloblastoma. Outcomes research, with specific emphasis on cost-effectivenes, quality of life and neurocognitive function has been another important area of activity.
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