Moritz Buenemann

BIOGRAPHY

ACADEMIC POSITION:
Full Professor for Pharmacology & Toxicology and Director of the Department of Pharmacology and Clinical Pharmacy at Philipps-University Marburg

EDUCATION:
• Diplom (Biology) University of Bochum, Germany
• Dr rer nat University of Bochum, Germany

MEMBERSHIPS:
• Member of the Biophysical Society
• Member of the German Society for Pharmacology and Toxicology (DGPT)
• Member of the German Pharmacytical Society (DPhG)

RESEARCH INTERESTS:
The Bünemann lab studies spatiotemporal dynamics and fundamental principles of coupling within G protein coupled signaling networks. We are specifically interested in the dynamics of GPCR activation, deactivation and desensitization as well as the dynamics and their mode of interaction with G proteins and arrestins. Furthermore we study dynamics of G protein subunit interaction with important effectors including adenylyl cyclases, PLCbeta and RhoGEF proteins. Many of our assays are based on Förster Resonance Energy Transfer (FRET) and fluorescence based mobility measurements which allow for high temporal resolution measurements in single cells. Some of our current efforts are devoted to unravel the mechanism of voltage dependence of GPCRs and probing the effect of membrane voltage on the pharmacology of these receptors.

HOME PAGE
http://www.uni-marburg.de/fb16/ipkp/gruppen/ag_buenemann