Bruno GoudMecanismes moleculaires du transport intracellulaire, Institut Curie, Paris, France F1000 Faculty Member (since 24 November 2008)
Research Director 1st class, CNRS
Our main research themes are briefly described below:
genetic view of the meiotic recombination, of the genome instability and repair
mechanisms governing various types of transport: nucleus-cytoplasm, cytoplasm, exo and endocytosis, phagocytose are currently under investigation using experimental models in order to identify molecular mechanisms involved in traffic and remodeling of the cytoskeleton
molecular motors should help to better understand principles and functioning: study of cellular morphogenesis involving research on centrosome, various components of the cytoskeleton and the cell surface
expression regulation of adhesion systems are under investigation: signal mechanisms involved in tumoral progression are studied in murin models and human tumors. In order to identify genes involved in tumoral progression that could be used as therapeutic targets, we work on functional genomic approaches and plan to create a bioinformatics pole.
A biologist and a physicist talk about a fruitful collaboration exploring the physics of membrane trafficking. [Video recorded 02 June 2011]
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F1000 Biology Reports 2011 3:(7) (01 Apr 2011)
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