Sebastian Amigorena

BIOGRAPHY

ACADEMIC POSITION:
Director of the Immunity and Cancer Unit

EDUCATION AND POSITIONS:
• 1984 'Maîtrise de Biochimie', University Paris VII, Biochemistry
• 1985-1990 PhD, Biochemistry, Immunology, University Paris VII, Paris, France
FcR expression in B lymphocytes, Laboratoire d'Immunologie Cellulaire et Clinique, Institut Curie, Paris
• 1990 'Chargé de Recherche', CNRS
• 1990-1992 Post-doctoral fellow, FcR structure and function in B lymphocytes, Laboratoire d'Immunologie Cellulaire et Clinique, Institut Curie, Paris
• 1992-1994 Postdoctoral Fellow, 'Cell biology of antigen presentation in B lymphocytes', Cell Biology Department, Yale University School of Medicine, New Haven, CT
• 1995-2003 Group leader, 'Cell biology of antigen presentation', Section Recherche, INSERM U520, Institut Curie, Paris
• 1999 'Directeur de Recherche”' CNRS
• 2003-2011 Director of INSERM Unit 932, Immunity and Cancer, Institut Curie, Paris
• 2010 'Directeur de Recherche de Classe Exceptionnelle', CNRS

RESEARCH INTERESTS:
• To understand how the intracellular traffick of MHC molecules determines antigen presentation in dendritic cells
• To analyse the effect of HIV infection on the intracellular transport of MHC molecules and on antigen presentation
• To study the biogenesis and biological functions of exosomes

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