Brett FinlayBiotechnology Laboratory, University of British Columbia, Vancouver, BC, Canada F1000 Section Head (since 13 July 2001)
Dr B Brett Finlay is a Professor in the Michael Smith Laboratories, and the Departments of Biochemistry and Molecular Biology, and Microbiology and Immunology at the University of British Columbia.
EDUCATION AND PREVIOUS POSITIONS:
He obtained a BSc (Honors) in Biochemistry at the University of Alberta, where he also did his PhD (1986) in Biochemistry under Dr William Paranchych, studying F-like plasmid conjugation. His post-doctoral studies were performed with Dr Stanley Falkow at the Department of Medical Microbiology and Immunology at Stanford University School of Medicine, where he studied Salmonella invasion into host cells. In 1989, he joined UBC as an Assistant Professor in the Biotechnology Laboratory.
He is well recognized internationally for his work, and has won several prestigious awards including the EWR Steacie Prize, the CSM Fisher Scientific Award, a MRC Scientist, five Howard Hughes International Research Scholar Awards, a CIHR Distinguished Investigator, BC Biotech Innovation Award, the Michael Smith Health Research Prize, the IDSA Squibb award, the Jacob Biely Prize, is a Fellow of the Royal Society of Canada and the Canadian Academy of Health Sciences, an Officer of Canada and awarded the Order of BC, and is the UBC Peter Wall Distinguished Professor.
He is a cofounder of Inimex Pharmaceuticals Inc, and Director of the SARS Accelerated Vaccine Initiative. He also serves on several editorial and advisory boards, and is a strong supporter of communicating science to the public.
Dr Finlays research interests are focussed on host-pathogen interactions, at the molecular level. By combining cell biology with microbiology, he has been at the forefront of the emerging field called Cellular Microbiology, making several fundamental discoveries in this field, and publishing over 300 papers. His laboratory studies several pathogenic bacteria, with Salmonella and pathogenic E. coli interactions with host cells being the primary focus.
Research in my lab is focussed on understanding bacterial pathogenesis from the perspective of both pathogen and host. In addition to studying the molecular mechanisms of pathogenicity for Salmonella and E. coli, we are interested in gaining further understanding of the critical human innate responses to microbial infection. By applying techniques from several disciplines including microbiology, cell biology, biochemistry, immunology, genomics and bioinformatics we have begun to understand the molecular mechanisms of microbial pathogenesis, ultimately allowing development of novel vaccines, diagnostics, and therapeutics that can be used to control infections caused by a wide range of globally important pathogens.
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F1000 Biology Reports 2011 3:(4) (01 Feb 2011)
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