Daniel RemickDepartment of Pathology and Laboratory Medicine, University of Boston, Boston, MA, USA F1000 Faculty Member (since 15 November 2005)
Professor and Chairman of Pathology and Laboratory Medicine
The laboratory focuses on investigating the inflammatory response with particular emphasis on cytokines. We are attempting to determine how the inflammatory response results in tissue/organ injury and death. To achieve this goal the laboratory uses a variety of methods ranging from whole animal models to isolated cells with reporter gene constructs. The ultimate focus of the lab is to understand the reaction to inflammation so that it may be modulated to improve health outcomes. It should be specifically noted that the modulation may include either blocking excessive inflammation or augmenting immunosuppression.
Common themes: The primary theme which ties together all of the projects is the careful measurement of cytokines. Cytokines are peptide mediators of the inflammatory response which represent critical components. They have been successfully modulated to improve health in patients with severe diseases.
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