Baidong Hou

BIOGRAPHY

Baidong Hou is an Associate Faculty Member who works with Faculty Member Anthony DeFranco to recommend the scientific literature in their field.

Education:

1989-1994: B.S., Beijing Medical University, Beijing, China

1994-1997: Medical Resident, Peking Union Medical College Hospital, Beijing, China

1997-2001: Ph.D., Peking Union Medical College, Beijing, China

2001-2003: Postdoctoral fellow, Vanderbilt University, Nashville, TN, USA

2003-2010: Postdoctoral fellow, University of California, San Francisco, CA, USA

2010.5 to present: Professor, Institute of Biophysics, Chinese Academy of Science,

Beijing, China, supported by CAS Hundred Talent Program

Research interests:

Host defense against invading microbes requires recognizing pathogen-associated molecular patterns and coordinated interactions between different immune cell types. The long-term goal of our research team is to understand how immune cells are activated by pathogens and how their functions are coordinated to eradicate the pathogen. The current research is focusing on how the signaling of Toll-like receptors (TLRs), a prototype of mammalian “pattern-recognizing” receptor family, activates immune response in vivo. The main research aims are to define the role of TLR signaling (1) in the immune response to pathogens; (2) in promoting gut homeostasis and mucosal immunity; (3) in autoimmune diseases.