Pharmacokinetics & Drug Delivery Recommendations
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The College of Pharmacy, University of Michigan, Ann Arbor, MI, USA
School of Pharmacy, University of California, San Francisco, San Francisco, CA, USA
Center for Cancer Research, Laboratory of Metabolism, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, USA
School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, UK
- » Drug delivery (incl. gene therapy and stem cells as delivery systems; blood-brain barrier; liposomes, polymers and drug delivery)
- » Drug-drug, drug-disease, drug-nondrug remedy Interactions
- » Metabolism (phase I and phase II enzymes)
- » Pharmacokinetics, pharmacodynamics and bioavailability
- » Therapeutic drug monitoring
- » Transporters plus biliary and renal elimination
The authors describe their discovery of a novel series of boronate inhibitors of beta-lactamase enzymes involved in resistance to carbapenem antibiotics. Their design is based on an extensive research history in boronate beta-lactamase...
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