In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development.
Proc Natl Acad Sci U S A. 2011 Feb 22; 108(8):3288-93
Andy Groves
26 Apr 2011
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Technical Advance
This is one of the first studies to use multiple complimentary techniques to identify the direct targets of a transcription factor. In the course of this work, the authors also identify a novel binding site consensus for the Atoh1 transcription factor, and present the surprising finding that Atoh1 directly regulates many aspects of...
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