Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity.
Nat Med. 2011 Apr; 17(4):479-87
Mark Doherty
21 Apr 2011
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New Finding
In the field of vaccinology, adjuvants have taken prominence as a hot field of research. This publication potentially answers a vexatious question -- the mechanism of action of alum, the grand-daddy of human adjuvants, which until now has remained unknown.
The adjuvant alum (potassium aluminum sulfate) has been used in human vaccines...
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