The crystal structure of a self-activating G protein alpha subunit reveals its distinct mechanism of signal initiation.
Sci Signal. 2011; 4(159):ra8
Nathan Dascal
24 Feb 2011
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Technical Advance
This paper uses a structural and functional approach to get a new and important insight into guanine nucleotide-binding protein (G protein) signaling mechanisms.
The authors solved the crystal structure of GPA1, a G{alpha} subunit of the plant Arabidopsis thaliana, which functionally differs from its animal counterparts by being...
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