Arthritis Rheum. 2011 Jan; 63:118-26
This study is quite remarkable for reporting that there is an intrinsic deviation of naive CD4+ T cells to become inflammatory T helper 17 (Th17) cells due to an alteration in transforming growth factor (TGF)-beta signal transduction in a mouse strain genetically susceptible to collagen-induced arthritis (CIA), a model for human rheumatoid...
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