Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice.
Immunity. 2010 Dec 14; 33(6):942-54
Sharma MD, Hou DY, Baban B, Koni PA, ..., Chandler PR, Blazar BR, Mellor AL, Munn DH. Sharma MD, Hou DY, Baban B, Koni PA, He Y, Chandler PR, Blazar BR, Mellor AL, Munn DH. Immunity. 2010 Dec 14; 33(6):942-54
This paper shows that the already identified ability of Foxp3+ Treg cells to convert to helper-like activity can - under some conditions - be swifter than that of conventional helper CD4+ T cells and aid generation of cross-primed CD8 T cells, thus further extending the extraordinary range of plasticity of Foxp3+ Treg cells. This...
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