Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice.
Immunity. 2010 Dec 14; 33(6):942-54
Sharma MD, Hou DY, Baban B, Koni PA, ..., Chandler PR, Blazar BR, Mellor AL, Munn DH. Sharma MD, Hou DY, Baban B, Koni PA, He Y, Chandler PR, Blazar BR, Mellor AL, Munn DH. Immunity. 2010 Dec 14; 33(6):942-54
This paper shows that the already identified ability of Foxp3+ Treg cells to convert to helper-like activity can - under some conditions - be swifter than that of conventional helper CD4+ T cells and aid generation of cross-primed CD8 T cells, thus further extending the extraordinary range of plasticity of Foxp3+ Treg cells. This...
Get instant access to Article Recommendations from more than 5,000 expert scientists and clinical researchers, assisted by 5,000 associates, by taking out a monthly subscription. The first month of your subscription will be free of charge.
Start your personal subscription today.
Subscribe for $9.95/monthSend a recommendation to your institution's librarian or information manager to request an extended free trial for all users.
Recommend to your LibrarianIf you are a librarian or information manager, you may request an extended free trial for your academic or corporate institution.
Request an Institutional Trialyour institution might be eligible for free access via our sponsorship scheme. Check our sponsorship page.
If you think you should be able to access this content, please contact us.