Translocation of surface-localized effectors in type III secretion.
Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1639-44
Akopyan K, Edgren T, Wang-Edgren H, Rosqvist R, Fahlgren A, Wolf-Watz H, Fallman M. Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1639-44
This paper is exceptional because it challenges the currently accepted and dogmatic 'conduit model', which claims that several pathogenic bacteria use type III secretion systems (T3SS) to translocate effector proteins from the bacterial cytosol into the host cell through a continuous channel built up by the T3SS upon bacterium-host...
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