HLA class I molecules partner with integrin beta4 to stimulate endothelial cell proliferation and migration.
Sci Signal. 2010; 3:ra85
Zhang X, Rozengurt E, Reed EF. Sci Signal. 2010; 3:ra85
This article merits reading because it characterizes a functional interaction between the beta4 integrin and human leukocyte antigens class I (HLA-I), and this interaction could impact HLA-I function in specific cell types.
The integrin alpha6beta4, often referred to as beta4 integrin, is arguably the most complex of the integrins...
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