Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.
Sci Signal. 2010 Dec; 3(153):rs4
Simon Hubbard
06 Jun 2012
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Technical Advance
This paper sets the standard for large-scale studies seeking to characterise the phosphoproteome of an organism, and demonstrates that quantitative phosphoproteomics can be carried out on a large scale. The results illustrate both the direct and indirect effects of kinases and phosphatases, and suggest that most phospho events are...
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