CD169-positive macrophages dominate antitumor immunity by crosspresenting dead cell-associated antigens.
Immunity. 2011 Jan 28; 34(1):85-95
Malini Raghavan and Natasha Del Cid
23 Jun 2011
This study brings new insights into relevant antigen presenting cell (APC) populations that cross-present apoptotic cell-associated antigens injected subcutaneously. Additionally, mechanisms of antigen uptake are addressed. Lastly, it is interesting that physical barriers (not mechanistic ones) and cell localization within the lymph...
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