Increased abundance of opioid receptor heteromers after chronic morphine administration.
Sci Signal. 2010; 3(131):ra54
Gupta A, Mulder J, Gomes I, Rozenfeld R, ..., Junek M, Cahill CM, Harkany T, Devi LA. Gupta A, Mulder J, Gomes I, Rozenfeld R, Bushlin I, Ong E, Lim M, Maillet E, Junek M, Cahill CM, Harkany T, Devi LA. Sci Signal. 2010; 3(131):ra54
This article provides a highly innovative approach towards examining G protein-coupled receptor (GPCR) heterodimers.
In this article, the authors developed antibodies capable of selectively recognizing the heterodimer of mu and delta receptors without recognizing either one alone. This is a very innovative and potentially valuable...
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