An efficient method for genome-wide polyadenylation site mapping and RNA quantification.
Nucleic Acids Res. 2013 Jan 7
Wilkening S, Pelechano V, Järvelin AI, Tekkedil MM, Anders S, Benes V, Steinmetz LM. Nucleic Acids Res. 2013 Jan 7
A new method to identify polyadenylation sites is now available. It has recently become obvious that alternative polyadenylation is a major way to regulate both protein diversity and gene expression. However, the proportion of reads specific to these regions is very low in data coming from RNA-seq runs. Several papers have already...
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