A hybrid G-quadruplex structure formed between RNA and DNA explains the extraordinary stability of the mitochondrial R-loop.
Nucleic Acids Res. 2012 Nov 1; 40(20):10334-44
Jim Maher
03 Jan 2013
|
Interesting Hypothesis, New Finding
At just over 16,500 base pairs, the mitochondrial genome of human cells is tiny. It remains vital by encoding tRNAs and oxidative phosphorylation enzymes whose genes have (mysteriously) not yet been shed to the nucleus. Regulation of the copy number of mitochondrial DNA within each mitochondrion is potentially important in disease...
INDIVIDUAL SUBSCRIPTIONS
Get instant access to Article Recommendations from more than 5,000 expert scientists and clinical researchers, assisted by 5,000 associates, by taking out a monthly subscription. The first month of your subscription will be free of charge.
Start your personal subscription today.
Subscribe for $9.95/monthINSTITUTIONAL SUBSCRIPTIONS
Send a recommendation to your institution's librarian or information manager to request an extended free trial for all users.
Recommend to your LibrarianIf you are a librarian or information manager, you may request an extended free trial for your academic or corporate institution.
Request an Institutional Trialyour institution might be eligible for free access via our sponsorship scheme. Check our sponsorship page.
If you think you should be able to access this content, please contact us.