Astrocytes modulate neural network activity by Ca²+-dependent uptake of extracellular K+.
Sci Signal. 2012 Apr 3; 5(218):ra26
Ken McCarthy and Daniel Bonder
12 Nov 2012
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Interesting Hypothesis, New Finding
This work identifies a novel way that astrocytes might modulate neuronal activity in vivo. Previous work focused on calcium-dependent release of neuro-active molecules (gliotransmitters) from astrocytes; this paper demonstrates the ability of astrocytes to modulate neuronal activity without the release of gliotransmitter. These...
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