Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions.
Nucleic Acids Res. 2012 Jul 19
Clotilde Théry and Elodie Segura
28 Sep 2012
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New Finding
Since the discovery in 2007 by the group of Lötvall {1} that exosomes, a subclass of secreted membrane vesicles, contain mRNA and micro RNA (miRNA), and can transfer this genetic information to other cells, a strong interest has emerged for this field. This observation suggested that exosomes represented a new, somehow unexpecte means...
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