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Somatostatin Analogs Modulate AIP in Somatotroph Adenomas: The Role of the ZAC1 Pathway.

Chahal HS, Trivellin G, Leontiou CA, Alband N ... Carlsen E, Wass JA, Grossman AB, Korbonits M Chahal HS, Trivellin G, Leontiou CA, Alband N, Fowkes RC, Tahir A, Igreja SC, Chapple JP, Jordan S, Lupp A, Schulz S, Ansorge O, Karavitaki N, Carlsen E, Wass JA, Grossman AB, Korbonits M J Clin Endocrinol Metab. 2012 Aug; 97(8):E1411-20

Ernesto De Menis and Paola Sartorato

16 Aug 2012 | New Finding

This article examines the role of the aryl hydrocarbon receptor interaction protein (AIP) in the mechanism of action of the somatostatin analogs (SAs) in the treatment of somatotroph adenomas. AIP is a co-chaperone protein with a tumor suppressor role. In the study, the authors show that the immunostaining of AIP protein in growth...

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Somatostatin Analogs Modulate AIP in Somatotroph Adenomas: The Role of the ZAC1 Pathway.

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