Differences in AMPA and kainate receptor interactomes facilitate identification of AMPA receptor auxiliary subunit GSG1L.
Cell Rep. 2012 Jun 28; 1(6):590-8
Stuart Cull-Candy and Ian Coombs
07 Aug 2012
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New Finding
AMPA receptors (AMPARs) are tetrameric ligand-gated ion channels that mediate a majority of fast information transfer within the brain. In vivo, these receptors are assembled as homomeric or heteromeric combinations of their primary subunits (GluA1-4). When heterologously expressed in vitro, the AMPAR subunits respond to the excitatory...
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