Positive roles for negative regulators in the mating response of yeast.
Mol Syst Biol. 2012; 8:586
Houser JR, Ford E, Nagiec MJ, Errede B, Elston TC Mol Syst Biol. 2012; 8:586
In this interesting paper, the authors investigate Ste12p-mediated transcriptional regulation of the yeast pheromone signaling network (mating response). Specifically, the authors utilized integrated computational and experimental approaches to generate an ordinary differential equation (ODE)-based mathematical model that not only...
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