Effect of daily sedative interruption on sleep stages of mechanically ventilated patients receiving midazolam by infusion.
Anaesth Intensive Care. 2011 May; 39(3):392-400
Oto J, Yamamoto K, Koike S, Imanaka H, Nishimura M. Anaesth Intensive Care. 2011 May; 39(3):392-400
This study demonstrates that daily sedative interruption is associated with increased slow-wave sleep and rapid eye movement sleep in mechanically ventilated patients compared to those on continuous sedation. Proper selection of and timing of sedation and analgesia are important to promote optimal sleep, sedation and pain control...
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