Secreted kinase phosphorylates extracellular proteins that regulate biomineralization.
Science. 2012 Jun 1; 336(6085):1150-3
Tagliabracci VS, Engel JL, Wen J, Wiley SE ... Kinch LN, Xiao J, Grishin NV, Dixon JE Tagliabracci VS, Engel JL, Wen J, Wiley SE, Worby CA, Kinch LN, Xiao J, Grishin NV, Dixon JE Science. 2012 Jun 1; 336(6085):1150-3
Phosphorylation is involved in the regulation of many biological processes, mainly in the cell interior. Although extracellular phosphorylation has been proposed in the past, its existence has not been sufficiently studied. In this paper, the authors identified a mammalian Golgi protein kinase as a secreted kinase, and elucidated...
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